Skip to content

emmaywei/Enhancer_dl

Repository files navigation

The environments:

  • All the prediction and deepshap with jupyter_tf (in environment.yml), and everything TF-modisco related with meme_env (meme.yml)

The models:

  • I have the zip files of all the models (the name should be with day e.g. D5 and domain e.g. pMN)
  • To use the model files, I have a script maybe_predict.py that saves the prediction in a csv file

  • The training example is in Training/example_usage.txt

Deep explainer:

  • deep_explainer/run_deepexplain_savenpz_corrected.py saves the contribution scores of the sequences
  • Can be used to visualisation

tf-modisco:

  • Requires npz file of the one hot encoded fasta
  • Command line modisco motifs in script modisco_and_meme/run_modisco_int_new1.sh, then compared to jaspar database using modisco_and_meme/submit_meme2.sh
  • To help produce understandable reports modisco_and_meme/Interpret_modisco.ipynb is used to extract motif names and find matching names from MA codes

Interaction analysis:

  • In the folder interaction_analysis
  • Bash script to run in interaction_analysis/interactiveD11.txt
  • (Implementation requires understanding the orientation of motif, impact of placement of motifs, distances between motifs)

About

No description, website, or topics provided.

Resources

Stars

Watchers

Forks

Releases

No releases published

Packages

No packages published