This is a repository that contains helpful notebooks and reference packages that can be used to perform difference imaging on non-HST images.
This is the sndrizpipe repository you will need to use when doing image processing for non-HST images: https://github.com/srodney/sndrizpipe The version available on 11/13/2020
As above, but this is for the drizzlepac you need: https://github.com/spacetelescope/drizzlepac The version that last worked is 3.2.0