The Xvarhet R package contains a collection of quantitative trait variance heterogeneity tests for X-chromosome SNPs.
The current release is: version 1.0 See "release" tab.
To install our R package "Xvarhet", you can either run in R directly:
install.packages("devtools") # if you have not installed already devtools::install_github("WeiAkaneDeng/Xvarhet")
To load the library in R, simply run in R:
library("Xvarhet")
Deng WQ, Mao S, Kalnapenkis A, Esko T, Mägi R, Paré G, Sun L. Analytical strategies to include the X-chromosome in variance heterogeneity analyses: Evidence for trait-specific polygenic variance structure. Genet Epidemiol. 2019 Oct;43(7):815-830. doi:10.1002/gepi.22247. Epub 2019 Jul 22. PMID: 31332826.
We are proud to announce the release of our integrated generalized Joint-Location-Scale (gJLS2) R package for genome-wide analysis (both autosomes and X-chromosome) through CRAN: https://cran.r-project.org/web/packages/gJLS2/index.html.
Thus, Xvarhet will no longer be updated and all functions (and more) can be done using the new gJLS2 package.