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Sam-E18/README.md

Hi, I'm Samuel Escudero

🧬 Biologist | Bioinformatics Researcher | Genomics

I'm a bioinformatics researcher with a background in genetics and molecular biology. My work sits at the intersection of computational genomics and health sciences I'm especially drawn to neuroscience, single-cell transcriptomics, and immune dysregulation in neurodegeneration.

🔬 Research Interests

  • Single-cell RNA sequencing (scRNAseq) analysis and immune cell profiling
  • Bulk RNA-seq differential expression and pathway analysis
  • Neuroinflammation and Alzheimer's disease genomics
  • Population genomics, GWAS, and genetic risk factor discovery
  • Comparative and evolutionary genomics

🛠️ Tools & Languages

Python R Bash Nextflow Git

Bioinformatics: Seurat · Scanpy · MAST · CellChat · DESeq2 · PLINK · UMAP/PCA
Wet lab: DNA/RNA extraction · PCR · Sequencing library prep

📫 Connect with me

LinkedIn Email

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  1. Python-Assignments-Bioinformatics Python-Assignments-Bioinformatics Public

    This is a space that shares the assignments from the Introduction to Python course focused on bioinformatics for health sciences. Most of the problems are focused on biological analysis.

    Python

  2. MSI_project_D2R_ETQ_2025 MSI_project_D2R_ETQ_2025 Public

    In this work, we focus on the dopamine D2 receptor (D2R) and its interactions with the antagonist eticlopride (ETQ) by studying its PDB structure and exploring two newly designed derivatives.

    R

  3. CLL_RNAseq_MultiplePipeline CLL_RNAseq_MultiplePipeline Public

    Repository to share CLL_RNAseq pipeline in three differents versions.

    HTML

  4. geopocket geopocket Public

    Forked from llorensvilla/geopocket

    GeoPocket is a geometry Python based binding site predictor that combines surface and cavity detection with residue interaction scoring.

    Python

  5. Bash_Toolkit_ALG Bash_Toolkit_ALG Public

    A curated collection of Bash scripts from the Algorithms and Linux Genomics course.

    Shell

  6. MGC29/PGB-Project MGC29/PGB-Project Public

    R