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Add ICC correction module#133

Merged
ammarcsj merged 1 commit into
add_quant_reader_and_table_updatesfrom
add_icc_correction
May 25, 2026
Merged

Add ICC correction module#133
ammarcsj merged 1 commit into
add_quant_reader_and_table_updatesfrom
add_icc_correction

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Summary

  • Adds icc_correction.py: estimates a global intraclass correlation (ICC) from null proteins and applies it as a design-effect correction to Stouffer z-score aggregation, improving calibration under correlated replicates
  • Includes full unit test suite

Notes

Part of the residual decorrelation PR stack. Stacked on #132.

Base automatically changed from add_intensity_summarization to add_quant_reader_and_table_updates May 25, 2026 09:09
@ammarcsj ammarcsj merged commit 9701197 into add_quant_reader_and_table_updates May 25, 2026
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@ammarcsj ammarcsj deleted the add_icc_correction branch May 25, 2026 09:10
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