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Gene Set Enrichment (PubWeb)

Workflow for performing gene set enrichment analysis from differential expression data

Input Data

The input data for this workflow must consist of two files, an input csv file and a GMT geneset reference file.

The input CSV file contains the

Input CSV Format

The input csv must be formatted as a CSV, with the file extension '.csv[.gz]', as appropriate.

The input csv must have at least 3 columns: one for the gene ID, a 'score' column showing relative expression levels for that gene (e.g. log2 fold change), and a p-value column. There may be additional columns in the csv, but they will be ignored in this analysis.

Genesets File

The .gmt file is a collection of gene sets, such as one of the MSigDB datasets.

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  • Nextflow 65.0%
  • Python 27.7%
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