Is it practical to use coded aperture for photography?

[MRYingLEE]

I am an amateur photographer with strong IT background.
I just wonder whether it is practical to use coded aperture for all-in-focus photos.

1. Is the final photo quality not worse than that without coded aperture for the focused area?
2. Is the shooting procedure convenient?
    Is it required to focus approximately before shooting? Can I just point and shoot without focus?
    Is the manual focus mode the only way to use coded aperture? In other words, can the built-in autofocus function of the camera still work?

Coded aperture is amazing. But I have never found someone uses it to take photos. Can you comment too?

Thank you in advance,

Ying