Feature request

[rimonparves]

It would be nice if you included a feature that generates a report highlighting regions with no transcription activity. When your model identifies regions with high transcription activity, it should also predict which mutations could shut down or slow transcription in those areas. This would make the data more useful and help users design constructs more effectively, with reasonable implications.

[hsalis]

Hello Rimon. The website (https://salislab.net/software) provides several interactive reporting formats (graphs, CSV). The Promoter Calculator in design mode carries out automated design of promoter sequences with targeted transcription rates at specific transcription start sites, using genetic algorithm optimization. In some of our other design algorithms, e.g. the CDS Calculator, the algorithm generates DNA sequences that do not contain undesired internal promoters, using the Promoter Calculator model for prediction.