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Copy file name to clipboardExpand all lines: Jacques_Murphy.qmd
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Gaussian distribution, this assumption is particularly poor when the
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measured counts are low. Instead, we use the reference
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distribution for count data which is the Poisson distribution
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[@Agresti_2002; @Inouye1998].
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[@Agresti_2002; @Inouye2017].
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When a data set is heterogeneous, clustering allows to extract
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homogeneous subsets from the whole data set. Many clustering methods,
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predictor variables, then the variable is called "redundant" and if the
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regression model has no predictor variables, then the variable is called
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"irrelevant".
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@fig-Running-result1 shows the cluster mean for each variable, where the
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label indicates if the variable is irrelevant for clustering ("I"),
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redundant ("R") or useful (the label is then the cluster number).
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@fig-Running-result1 shows the cluster mean for each variable, where the label indicates if the variable is irrelevant for clustering (“I”), redundant (“R”) or useful (then the point is unlabelled).
abstract = {The Poisson distribution has been widely studied and used for modeling univariate count-valued data. However, multivariate generalizations of the Poisson distribution that permit dependencies have been far less popular. Yet, real-world, high-dimensional, count-valued data found in word counts, genomics, and crime statistics, for example, exhibit rich dependencies and motivate the need for multivariate distributions that can appropriately model this data. We review multivariate distributions derived from the univariate Poisson, categorizing these models into three main classes: (1) where the marginal distributions are Poisson, (2) where the joint distribution is a mixture of independent multivariate Poisson distributions, and (3) where the node-conditional distributions are derived from the Poisson. We discuss the development of multiple instances of these classes and compare the models in terms of interpretability and theory. Then, we empirically compare multiple models from each class on three real-world datasets that have varying data characteristics from different domains, namely traffic accident data, biological next generation sequencing data, and text data. These empirical experiments develop intuition about the comparative advantages and disadvantages of each class of multivariate distribution that was derived from the Poisson. Finally, we suggest new research directions as explored in the subsequent Discussion section. WIREs Comput Stat 2017, 9:e1398. doi: 10.1002/wics.1398 This article is categorized under: Statistical and Graphical Methods of Data Analysis > Multivariate Analysis},
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year = {2017}
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}
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@article{Rau2015,
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author = {Rau, Andrea and Maugis-Rabusseau, Cathy and Martin-Magniette, Marie-Laure and Celeux, Gilles},
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title = "{Co-expression analysis of high-throughput transcriptome sequencing data with Poisson mixture models}",
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