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<!DOCTYPE html>
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<title>Publications · Brent Y. Chick</title>
<meta name="description" content="Peer-reviewed publications by Brent Y. Chick.">
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<h1 class="name"><a href="index.html">Brent Y. Chick</a></h1>
<p class="tagline">PhD Candidate · Salk Institute · La Jolla, CA</p>
<nav class="primary">
<!-- Blog: re-enable once first Substack post is live -->
<!-- <a href="https://substack.com/@bchick" target="_blank" rel="noopener">Blog</a> -->
<a href="research.html">Research</a>
<a href="publications.html" class="current">Publications</a>
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<div class="contact">
<a href="mailto:bchick@salk.edu">Email</a>
<a href="Brent_Chick_Resume.pdf" target="_blank" rel="noopener">CV</a>
<a href="https://scholar.google.com/citations?user=QQkDZcAAAAAJ&hl=en" target="_blank" rel="noopener">Scholar</a>
<a href="https://github.com/bchick" target="_blank" rel="noopener">GitHub</a>
<a href="https://www.linkedin.com/in/brent-chick-50898075/" target="_blank" rel="noopener">LinkedIn</a>
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<p class="lead">
Selected peer-reviewed publications. Full list on
<a href="https://scholar.google.com/citations?user=QQkDZcAAAAAJ&hl=en" target="_blank" rel="noopener">Google Scholar</a>.
</p>
<ul class="pubs">
<li>
<p class="title"><a href="https://doi.org/10.1038/s41586-025-09989-7" target="_blank" rel="noopener">Atlas-guided discovery of transcription factors for T cell programming</a></p>
<p class="meta">
Chung HK, Chen S, Engel BJ, Bhatt RR, Li Y, Fang Q, Yang S, Zhang C, Coles GL, Bhatt DL, Pan X, Li Y, Li T, Rathore APS, Wen D, Adachi K, Song L, <span class="self">Chick BY</span>, Hargreaves DC, Zhang K, Bhatt DL, Wang W. <em>Nature</em>, 2026.
</p>
</li>
<li>
<p class="title"><a href="https://doi.org/10.1101/2025.11.12.688147" target="_blank" rel="noopener">The antiviral interferon pathway drives astrocyte aging and motor decline</a></p>
<p class="meta">
Labarta-Bajo L, Bhatt DL, Bhatt RR, Ye H, <span class="self">Chick BY</span>, Hargreaves DC, Allen NJ. <em>bioRxiv</em>, 2025.
</p>
</li>
<li>
<p class="title"><a href="https://doi.org/10.1038/s41588-023-01628-z" target="_blank" rel="noopener">RNA polymerase II promoter-proximal pausing promotes BAF chromatin binding and remodeling</a></p>
<p class="meta">
<span class="self">Chick BY</span>, Hargreaves DC. <em>Nature Genetics</em>, 2024 (invited commentary).
</p>
</li>
<li>
<p class="title"><a href="https://doi.org/10.1016/j.immuni.2023.05.005" target="_blank" rel="noopener">Canonical BAF complex activity shapes the enhancer landscape that licenses CD8⁺ T cell effector and memory fates</a></p>
<p class="meta">
McDonald B†, <span class="self">Chick BY</span>†, Ahmed MY, Burns E, Ma S, Casero D, Bhatt DL, Kaech SM. <em>Immunity</em>, 2023 (†co-first author).
</p>
</li>
<li>
<p class="title"><a href="https://doi.org/10.59249/AXGU7370" target="_blank" rel="noopener">Early chromatin remodeling events in acutely stimulated CD8⁺ T cells</a></p>
<p class="meta">
McDonald B†, <span class="self">Chick BY</span>†, Hargreaves DC, Kaech SM. <em>Yale Journal of Biology and Medicine</em>, 2023 (†co-first author).
</p>
</li>
<li>
<p class="title"><a href="https://doi.org/10.1038/s41594-022-00858-9" target="_blank" rel="noopener">Switching under selection: how CoREST controls endocrine therapy resistance in ER+ breast cancer</a></p>
<p class="meta">
<span class="self">Chick BY</span>, Hargreaves DC. <em>Nature Structural & Molecular Biology</em>, 2022 (invited commentary).
</p>
</li>
<li>
<p class="title"><a href="https://doi.org/10.1016/j.celrep.2020.108320" target="_blank" rel="noopener">In vitro recapitulation of murine thymopoiesis from single hematopoietic stem cells</a></p>
<p class="meta">
Montel-Hagen A, Sun V, Casero D, Tsai S, Zampieri A, Jackson N, Li S, Lopez S, Zhu Y, <span class="self">Chick B</span>, He C, de Barros SC, Seet CS, Crooks GM. <em>Cell Reports</em>, 2020.
</p>
</li>
<li>
<p class="title"><a href="https://www.jimmunol.org/content/205/9/2483.abstract" target="_blank" rel="noopener">Pleiotropic roles of VEGF in the microenvironment of the developing thymus</a></p>
<p class="meta">
de Barros SC, Suterwala BT, He C, Ge S, <span class="self">Chick B</span>, Blumberg GK, Kim K, Klein S, Zhu Y, Wang X, Casero D, Crooks GM. <em>The Journal of Immunology</em>, 2020.
</p>
</li>
<li>
<p class="title"><a href="https://doi.org/10.1016/j.stem.2018.12.011" target="_blank" rel="noopener">Organoid-induced differentiation of conventional T cells from human pluripotent stem cells</a></p>
<p class="meta">
Montel-Hagen A, Seet CS, Li S, <span class="self">Chick B</span>, Zhu Y, Chang P, Tsai S, Sun V, Lopez S, Chen HC, He C, Chin CJ, Casero D, Crooks GM. <em>Cell Stem Cell</em>, 2019.
</p>
</li>
<li>
<p class="title"><a href="https://www.exphem.org/article/S0301-472X(18)30440-5/fulltext" target="_blank" rel="noopener">Notch signaling regulates the differentiation of CLEC9A+ dendritic cells (cDC1) from human and mouse hematopoietic stem/progenitor cells</a></p>
<p class="meta">
Seet CS, Li S, <span class="self">Chick B</span>, Casero D, Kim J, Gschweng E, Chen HC, Zhu Y, Lopez S, Miao R, Montel-Hagen A, Kohn D, Sehl M, Crooks GM. <em>Experimental Hematology</em>, 2018.
</p>
</li>
<li>
<p class="title"><a href="https://www.nature.com/articles/nmeth.4237" target="_blank" rel="noopener">Generation of mature T cells from human hematopoietic stem and progenitor cells in artificial thymic organoids</a></p>
<p class="meta">
Seet CS, He C, Bethune MT, Li S, <span class="self">Chick B</span>, Gschweng EH, Zhu Y, Kim K, Kohn DB, Baltimore D, Crooks GM, Montel-Hagen A. <em>Nature Methods</em>, 2017.
</p>
</li>
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<span>© 2026 Brent Y. Chick</span>
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<a href="mailto:bchick@salk.edu">bchick@salk.edu</a>
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