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  <title>Brent Y. Chick</title>
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      <h1 class="name"><a href="index.html">Brent Y. Chick</a></h1>
      <p class="tagline">PhD Candidate · Salk Institute · La Jolla, CA</p>

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        Hi, I'm Brent. My work sits at the intersection of chromatin biology, cell signaling, and computation.
        I'm a PhD candidate at the <a href="https://www.salk.edu/" target="_blank" rel="noopener">Salk Institute</a>
        in <a href="https://hargreaveslab.salk.edu/" target="_blank" rel="noopener">Diana Hargreaves' lab</a>, where I study how
        BAF (mSWI/SNF) chromatin remodeling complexes interpret cellular signals to control cell fate.
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      <p>
        Fascinated by chromatin's ability to buffer noise and encode memory, I aim to understand and leverage these properties
        to develop new approaches to cell engineering and therapeutic design. My research has been published in
        <em>Nature</em>, <em>Nature Methods</em>, <em>Cell Stem Cell</em>, <em>Cell Reports</em>, <em>The Journal of Immunology</em>,
        and others, with first-author research papers in <em>Immunity</em> and the <em>Yale Journal of Biology and Medicine</em>,
        and invited commentary in <em>Nature Genetics</em> and <em>Nature Structural &amp; Molecular Biology</em>.
      </p>

      <p>
        Before Salk, I did my MA at <a href="https://mcdb.ucsb.edu/" target="_blank" rel="noopener">UCSB</a> with
        <a href="https://labs.mcdb.ucsb.edu/wilson/max/" target="_blank" rel="noopener">Max Wilson</a>, using
        optogenetic tools to interrogate signaling dynamics. Earlier, I worked with
        <a href="https://crookslab.mednet.ucla.edu/" target="_blank" rel="noopener">Gay Crooks</a> and
        Chris Seet at UCLA on stem cell-derived T cell development, contributing to the
        <a href="https://www.nature.com/articles/nmeth.4237" target="_blank" rel="noopener"><em>Nature Methods</em> paper</a>
        describing artificial thymic organoids and follow-up work in
        <a href="https://doi.org/10.1016/j.stem.2018.12.011" target="_blank" rel="noopener"><em>Cell Stem Cell</em></a>
        and <a href="https://doi.org/10.1016/j.celrep.2020.108320" target="_blank" rel="noopener"><em>Cell Reports</em></a>.
        I started in research as an undergraduate at UCSD in
        <a href="https://biology.ucsd.edu/research/faculty/shedrick" target="_blank" rel="noopener">Stephen Hedrick's lab</a>.
      </p>

      <p>
        I'm joining industry in 2027 with a focus on epigenetic engineering, cell therapy,
        and AI×bio companies in the Bay Area. If you're working on hard, interesting problems in any of those areas,
        I'd love to <a href="mailto:bchick@salk.edu">get in touch</a>.
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      <span>© 2026 Brent Y. Chick</span>
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