It's ironic that the software for configuring this ultra-powerful keyboard uses absolutely none of this (or any other) keyboard's features to make the software easier to use.

Implement keyboard shortcuts for all functionality (or maybe just some, at first). For example, if there were hotkeys to select each color, say 1 to 0 and Shift+ 1 to 0 or something like that, I wouldn't have to tediously move my mouse all the way from the keyboard graphic to the color selection graphic, and back again.
I'd be happy with hotkeys for only the color selection and the function selection, frankly; I could use those for selecting, and then mouse clicks, to apply the selected color or function. That would dramatically streamline the experience by removing most of all that long-distance mouse movement. You might even consider allowing us to assign color OR function to a key (without changing tabs) by using the right button to apply color, and the left to apply function. (Or something like that. Maybe just another hotkey, to toggle between application of color and function.)