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Anjaney10/README.md

From Molecules to Medicine

A passionate researcher building a healthier future

  • I have over 4 years of research experience in academia and industry.
  • I enjoy building tools and deciphering complex, data-driven questions in biological systems.
  • My background combines bioengineering, bioinformatics, and molecular biology, which allows me to move comfortably between biological questions and scalable data workflows.

I am interested in roles where I can contribute to:

  • Multi-omics integration
  • Machine learning for biological data
  • Reproducible scientific computing
  • Cloud/HPC-based analysis pipelines

Technical Toolkit

Command Line Tools

Bash NextFlow SAMtools BCFtools GATK STAR Salmon

Protein Structure Modeling

ColabFold SWISS--MODEL RoseTTAFold

Python Libraries

Python BioPython Scikit--learn Seaborn SciPy Matplotlib Pandas NumPy ScanPy SquidPy PyTorch

R Packages

R ggplot2 Seurat survival DESeq2 edgeR GSVA GeomxTools gProfileR tidyverse


Featured Projects

1. Spatial Transcriptomics Analysis Platform

Built spatial_analyser, a high-performance web application for interactive analysis and visualization of single-cell and spatial transcriptomics data. The platform provides rapid computational workflows with intuitive visualization interfaces, enabling researchers to explore complex biological systems at cellular resolution.

Highlights

  • Developed a responsive web application for spatial transcriptomics data exploration
  • Implemented high-performance Python backend for rapid data processing and statistical analysis
  • Designed interactive HTML/JavaScript frontends for multi-dimensional data visualization
  • Built workflows to handle large-scale single-cell and spatial datasets efficiently
  • Integrated visualization tools for spatial coordinate mapping and gene expression analysis
  • Optimized data pipeline for real-time interactive analysis and rapid insights generation

Tech: Python HTML Web Application Spatial Transcriptomics Single-Cell Analysis Data Visualization Interactive Analytics Bioinformatics

View Repository


2. Gene Regulatory Network Visualization

Developed a comprehensive tool for visualizing and interpreting gene regulatory networks (GRNs). This project enables researchers to explore complex regulatory relationships between genes, providing insights into biological mechanisms and system-level behavior through sophisticated graph visualization and analysis.

Highlights

  • Built a Python-based tool for GRN graph construction and analysis
  • Implemented network visualization algorithms for complex biological networks
  • Designed a scalable architecture to handle large-scale regulatory network data
  • Created interactive visualization components for exploring gene-gene regulatory relationships
  • Developed computational workflows for network analysis and topology characterization
  • Engineered solutions for visualizing multi-level regulatory hierarchies and feedback loops

Tech: Python Network Analysis Graph Visualization Gene Regulation Systems Biology Bioinformatics Data Structures Computational Biology

View Repository


3. Master's Thesis: Cancer Systems Biology

Completed original research in computational cancer biology as part of Prof. Mohit Kumar Jolly's "Cancer Systems Biology" lab at IISc, Bengaluru. The thesis explores systems-level understanding of cancer dynamics through computational modeling, statistical analysis, and data-driven insights.

Highlights

  • Conducted comprehensive computational analysis using Jupyter Notebooks for reproducible research
  • Implemented statistical models and bioinformatics workflows in R for data analysis
  • Developed sophisticated visualizations for complex biological systems and mechanisms
  • Performed large-scale data processing and interpretation for cancer biology datasets
  • Integrated computational and experimental insights for systems-level understanding
  • Maintained rigorous documentation and reproducible computational workflows throughout research

Tech: Jupyter Notebook R Statistical Analysis Cancer Biology Systems Biology Computational Biology Data Science Scientific Computing IISc Bengaluru Research

View Repository


Let's Connect!

I combine biology expertise with strong software engineering practices, making me ideal for bioinformatics and research software roles.

  • Biology & Domain Knowledge: Genomics, transcriptomics, structural biology, molecular biology
  • Software Skills: Clean code, documentation, testing, maintainable tools
  • Scalable Computing: HPC, SLURM, Docker, AWS, large-scale data processing
  • Collaboration & Communication: Cross-disciplinary teamwork, technical writing, presentations

Interested in: Bioinformatics | Computational Biology | ML for Biology/Healthcare | Research Software Engineering


Credits: Adapted from https://github.com/misaell2/misaell2

Pinned Loading

  1. Master-Thesis Master-Thesis Public

    Master's thesis (original work) done in Prof. Mohit Kumar Jolly's "Cancer Systems Biology" lab at IISc, Bengaluru (INDIA)

    Jupyter Notebook

  2. spatial_analyser spatial_analyser Public

    Spatial-Analyser is a high-performance, interactive web application built for the rapid analysis and visualization of single-cell and spatial transcriptomics data.

    Python

  3. GRN-Visualization GRN-Visualization Public

    A tool for visualizing gene regulatory networks

    Python

  4. Soil-Communities-Response-to-Heat-Extreme-UniBern Soil-Communities-Response-to-Heat-Extreme-UniBern Public

    Forked from EvoNerd/Xtreme_heat

    HTML

  5. interconnected-axes-of-phenotypic-plasticity interconnected-axes-of-phenotypic-plasticity Public

    Forked from i-donno-riteshkm/Interconnected-axes-of-phenotypic-plasticity

    Codes for network and RACIPE simulations analysis for the paper. Title: "Interconnected axes of phenotypic plasticity drive coordinated cellular behaviour and worse clinical outcomes in breast canc…

    Jupyter Notebook

  6. MS_Thesis_Training MS_Thesis_Training Public

    Training work in Prof. Mohit Kumar Jolly's Lab at IISc, Bengaluru

    Jupyter Notebook